Due the rarity of lung transplantation, the field often lacks clear evidence to guide donor selection, perioperative management and posttransplant practices. In a recent Special Report published in the Journal of Heart and Lung Transplantation, Lung Transplant Consortium (LTC) leaders shared their strategies for maximizing use of the consortium and advancing lung transplantation.

The authors distilled key themes from the LTC Steering Committee Meeting in April – including how to leverage data elements from the PROMISE Lung Study, from biomarkers to PROs; clinical syndrome and consensus definitions; variation in management and management strategies; and future interventional trials leveraging the PROMISE consortium.

“Through analysis of the PROMISE study cohort, which already has enrolled nearly 1000 participants, our research will inform and guide best clinical practices improving care for patients with lung disease and that undergo lung transplant,” said LTC MPI Scott Palmer.

This is the first major publication to come out of the Lung Transplant Consortium, which was established in 2022 to serve as a research platform for rigorous observational and mechanistic studies in lung transplant. The Journal of Heart and Lung Transplantation is the official publication of the International Society for Heart and Lung Transplantation.

The report was a collaborative effort involving members from every corner of the consortium, from MPIs Megan Neely and Jason Christie and DCRI’s Allyn Damman to Steering Committee Cochairs Bryan Whitson and Ramsey Hachem.

Congratulations to the Lung Transplant Consortium investigators and Steering Committee on reaching this milestone!

Read the publication.

Contributors to the white paper included LTC MPIs Megan Neely, Scott Palmer, and Jason Christie; NHLBI Program Officer Emmanuel Mongodin, PhD; Bryan Whitson, MD, PhD; Ramsey Hachem, MD; Michaela Anderson, MD, MS; Courtney Frankel, MS; Michelle Oyster, MS; Ciara Shaver, MD, PhD; Eric Morrell, MD, MA; Meghan Aversa, MD; Allyn Damman, MA; and LTC DCC MPIs Megan Neely, PhD, Scott Palmer, MD, MHS, and Jason Christie, MD, MSCE.